Exosomes Aid in Repairing Skin Aging Caused by UV Radiation

Referenced from: International Journal of Molecular Medicine

Skin aging is characterized by roughness, laxity, dullness, as well as the appearance of spots and wrinkles. The primary cause of skin aging is prolonged exposure to excessive ultraviolet (UV) rays. Overexposure to UV rays stimulates the production of free radicals, leading to wrinkles, spots, and dullness. Therefore, it is essential to use sunscreen and engage in proper skincare to prevent and repair the signs of skin aging.

This piece shares insights into whether exosomes can help repair skin aging caused by UV radiation.

The research team first extracted and purified exosomes (referred to as BJ-5ta Exo). They then conducted animal experiments, irradiating the backs of mice with UV rays (every two weeks for eight weeks) and injecting 100 µl of exosomes (BJ-5ta Exo) under the skin of the mice each week of irradiation.

Observing the skin condition of the mice after eight weeks, the results showed that the epidermis of the UV-irradiated mice significantly thickened, with an increase in wrinkles and rougher skin. However, after injecting the exosomes (BJ-5ta Exo), the thickness of the mice’s epidermis gradually decreased, wrinkles significantly reduced, and the skin became smoother.

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